Whilst reduced-depend MBL hardly ever progresses to CLL, high-rely MBL progresses to CLL requiring therapy at a amount of one% to 2% a year. Superior-count MBL is distinguished from Rai 0 CLL based upon whether or not the B-mobile rely is over or beneath five × 109/L. Whilst people today with both equally substantial-depend MBL and CLL Rai phase 0